All compounds sold on this site are research-grade materials intended exclusively for in-vitro laboratory research by qualified professionals.
KPV is the active 3-amino-acid portion of α-MSH (lysine–proline–valine). Lab studies have looked at how it affects inflammation-signalling pathways inside cells. Research in gut-inflammation models has looked at how it is absorbed in the digestive tract and how it changes inflammation markers there.
Identity
Lys-Pro-Val · CAS 67727-97-3
C16H30N4O4 · ≥99% HPLC · 10 mg · 3 mL vial
Research on KPV (Lys-Pro-Val) investigates the C-terminal tripeptide fragment of α-melanocyte-stimulating hormone. In-vitro studies characterise its inhibition of NF-κB activation and pro-inflammatory cytokine signalling, and in-vivo work in murine colitis models examines its uptake via the PepT1 di/tripeptide transporter and effects on intestinal inflammation in DSS- and TNBS-induced disease. Subsequent animal studies further investigate the PepT1/KPV axis in the context of colitis-associated tumour development.
References
Reconstitution & storage
Reconstitute with bacteriostatic or sterile water to the concentration required by the researcher’s own protocol. Lyophilised: store at 2–8 °C, protected from light; refer to the lot CoA for the expiration date. Reconstituted: refrigerate at 2–8 °C and use within the researcher’s validated window; hold at −20 °C for longer-term storage.
Documentation — batch Certificate of Analysis (HPLC, third-party) provided for the lot shipped.
For Research Use Only. Not for Human or Veterinary Use. Not a drug, food, or supplement; not evaluated by the FDA; not intended for human or animal use.
